Scientific Conferences on Whole-Body Diffusion
Whole-Body Diffusion (DWB) is a diagnostic technique based on Magnetic Resonance imaging, which is relatively “young” from a medical and scientific point of view. It came into being in 2006 and its clinical applications have been developed since 2009 mainly in Italy (at the European Institute of Oncology – IEO, Milan) and in Great Britain. At the ASC in Castelli Calepio (Bergamo), we have accumulated one of the highest case loads of healthy subjects undergoing this examination for early cancer detection.
In just over a decade, DWB has gained international scientific prominence, thanks to studies published in the most important scientific journals, which have demonstrated its diagnostic effectiveness.
In 2021, the International Guidelines on DWB were published, which means that this diagnostic procedure has been accepted and shared by scientists worldwide. DWB has also been included in the international guidelines for the diagnosis and surveillance of various cancers.
Prof Giuseppe Petralia, Associate Professor at the University of Milan, Chief physician of the Precision Imaging and Research Unit at the European Institute of Oncology (IEO) in Milan and scientific advisor to ASC, is one of the leading experts on DWB and has published numerous scientific studies and lectured at national and international congresses.
Prof Giuseppe Petralia
A scientific publication is the main means of communication within the scientific community. It is a paper on a scientific topic, written in an objective way by scientists or technicians, which highlights in a transparent and verifiable manner the method and the research results. Its publication typically takes place in academic journals and other communication channels of the scientific community, but only once validated by peer review to become part of the scientific literature
Title: Psychological characteristics and satisfaction for the whole-body MRI in cancer screening
Year: 2022 Sep
PMID: 36148490 DOI: 10.1080/13548506.2022.2126989
Title: Oncologically Relevant Findings Reporting and Data System (ONCO-RADS): Guidelines for the Acquisition, Interpretation, and Reporting of Whole-Body MRI for Cancer Screening. Radiology.
Year: 2021 Jun
299(3):494-507. doi: 10.1148/radiol.2021201740. Epub 2021 Apr 27. PMID: 33904776.
Title: Value Attribution in the Decision to Use of Whole Body MRI for Early Cancer Diagnosis. Diagnostics (Basel).
Year: 2021 May 28
11(6):972. doi: 10.3390/diagnostics11060972. PMID: 34071199; PMCID: PMC8227751.
Title: Effects of Sex and Age on Fat Fraction, Diffusion-Weighted Image Signal Intensity and Apparent Diffusion Coefficient in the Bone Marrow of Asymptomatic Individuals: A Cross-Sectional Whole-Body MRI Study. Diagnostics (Basel).
Year: 2021 May 20
11(5):913. doi: 10.3390/diagnostics11050913. PMID: 34065459; PMCID: PMC8161193.
Title: Semi-Automated Segmentation of Bone Metastases from Whole-Body MRI: Reproducibility of Apparent Diffusion Coefficient Measurements. Diagnostics (Basel).
Year: 2021 Mar
11;11(3):499. doi: 10.3390/diagnostics11030499. PMID: 33799913; PMCID: PMC7998160.
Title: Preliminary observations regarding the expectations, acceptability and satisfaction of whole-body MRI in self-referring asymptomatic subjects. Br J Radiol.
Year: 2021 Feb 1
94(1118):20191031. doi: 10.1259/bjr.20191031. Epub 2020 Dec 1. PMID: 33237810; PMCID: PMC7934315.
Title: Whole-body magnetic resonance imaging: technique, guidelines and key applications. Ecancermedicalscience.
Year: 2021 Jan 7;15:1164. doi: 10.3332/ecancer.2021.1164. PMID: 33680078; PMCID: PMC7929776. https://ecancer.org/en/journal/article/1164-whole-body-magnetic-resonance-imaging-technique-guidelines-and-key-applications
Title: What’s New for Clinical Whole-body MRI (WB-MRI) in the 21st Century. Br J Radiol.
Year: 2020 Nov; 1;93(1115):20200562.
doi: 10.1259/bjr.20200562. Epub 2020 Sep 9. PMID: 32822545.
Title: Whole-body magnetic resonance imaging (WB-MRI) reporting with the METastasis Reporting and Data System for Prostate Cancer (MET-RADS-P): inter-observer agreement between readers of different expertise levels. Cancer Imaging.
Year: 2020 Oct 27; 20(1):77
doi: 10.1186/s40644-020-00350-x. PMID: 33109268; PMCID: PMC7590732.
Title: MRI for Rectal Cancer Primary Staging and Restaging After Neoadjuvant Chemoradiation Therapy: How to Do It During Daily Clinical Practice.
Year: 2020 Aug 29
Title: Pathological findings at radical prostatectomy of biopsy naïve men diagnosed with MRI targeted biopsy alone without concomitant standard systematic sampling.
Year: 2020 Jun 26
Title: Whole-body magnetic resonance imaging (WB-MRI) for cancer screening in asymptomatic subjects of the general population: review and recommendations.
Year: 2020 May
Title: Low PI-RADS assessment category excludes extraprostatic extension (≥pT3a) of prostate cancer: a histology-validated study including 301 operated patients.
Year: 2019 Oct; 29(10).
Title: Multiparametric Magnetic Resonance Imaging Second Opinion May Reduce the Number of Unnecessary Prostate Biopsies: Time to Improve Radiologists’ Training Program?
Year: 2019 Apr; 17(2).
Title: Reirradiation for isolated local recurrence of prostate cancer: Mono-institutional series of 64 patients treated with salvage stereotactic body radiotherapy (SBRT).
Year: 2019 Feb; 92(1094).
Title: The added value of whole-body magnetic resonance imaging in the management of patients with advanced breast cancer.
Year: 2018 Oct 12; 13(10).
Title: Multimodal image registration for the identification of dominant intraprostatic lesion in high-precision radiotherapy treatments.
Year: 2017 Nov; 90(1079).
Title: Rationale and protocol of AIRC IG-13218, short-term radiotherapy for early prostate cancer with concomitant boost to the dominant lesion.
Year: 2016 Oct 13; 102(5).
Title: Primary focal prostate radiotherapy: Do all patients really need whole-prostate irradiation?
Year: 2016 Sep; 105:100-11.
Year: 2015 Feb; 274(2).
Title: Diagnostic value of whole-body diffusion-weighted magnetic resonance imaging for detection of primary and metastatic malignancies: A meta-analysis.
Year: 2014 Feb; 83.
Title: Whole-body diffusion-weighted imaging: is it all we need for detecting metastases in melanoma patients?
Year: 2013 Dec; 23(12).
Title: Combined ultrasmall superparamagnetic particles of iron oxide-enhanced and diffusion-weighted magnetic resonance imaging facilitates detection of metastases in normal-sized pelvic lymph nodes of patients with bladder and prostate cancer.
Year: 2013 Dec; 64(6).
Title: Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls. AJR Am J Roentgenol.
Year: 2012 Aug; 199(2).
Title: Diagnosis of bone metastases: a meta-analysis comparing 18FDG PET, CT, MRI and bone scintigraphy.
Year: 2011; 21.
Title: Whole-body diffusion-weighted magnetic resonance imaging.
Title: Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations.
Year: 2009 Feb; 11(2).
Title: MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders.
Year: 1986 Nov; 161(2).
The story of ASC Italia in book form
The magic box against cancer (Mind Edizioni), written by Dr Giuseppe Petralia, tells the scientific story of the development of DWB, its recent establishment at the European Institute of Oncology in Milan and the birth of ASC Italia, the only facility in Europe that offers this examination to the healthy population.
The book is also an opportunity to take stock of all the useful avenues for cancer prevention in general and early diagnosis, which truly remains the winning weapon for nipping cancers in the bud.
“After reading this book, you too will be convinced of the value of DWB. Join us so that as many people as possible can benefit from it!” Anwar Padhani – Institute of Cancer Research in London – World’s leading expert on DWB and member of the Scientific Committee of ASC Italia